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Systematic Reviews

This guide provides a step-by-step breakdown of how to conduct a systematic review and how librarians can assist in the process.

Research Question Development

The purpose of a systematic review is to answer a specific research question. Research question frameworks, such as PICO, can help you to focus and develop the research question as well as identify the primary search terms. 

PICO Elements Considerations
P Patients/Populations/Problems Demographics, Problem Type, Diagnosis
I Intervention/Exposure Therapeutic, Preventative, Diagnostic, Time, Exposure
C Control/Comparison Placebo, Standard of Care, Preventative Measures, Not Applicable
O Outcome Measure Mortality Rate, Measure of Test, Rate of Disease Progression, Resolution

When formatting your question using the PICO format, consider: 

  • Demographic variables can include: age, gender, ethnicity, socioeconomic status in addition to health status. 
  • Comparison is not always an element within the PICO format.
  • Outcomes measure a positive impact on the patient/population/problem and should be measurable
  • Using the PICO format to develop a searchable & answerable question will provide the elements needed to obtain the best evidence from rigorous studies with statistically relevant findings. 

Additional clinical question frameworks

PEO = Population, Exposure, Outcome

PIE = Population, Intervention, Effect

FINER = Feasibility, Interesting, Novel, Ethical, Relevant

SPICE = Setting, Perspective, Intervention, Comparison, Evaluation

SPIDER = Sample, Phenomena of Interest, Design, Evaluation, Research Type

For assistance with question development, please contact the librarians: libmo@atsu.edu or libaz@atsu.edu

Exemplar Articles

What are exemplar articles?

Exemplar articles provide a foundational example of the type of studies to be included within the systematic review. These articles meet the eligibility criteria and answer the research question. 

Why are exemplar articles required

These types of articles provide the guidance for the search strategy development and the screening process. 

How do I acquire exemplar articles

Exemplar articles can be acquired through literature review. Check out some of the tools listed in the next tab.

*Note: Alternate terms for "exemplar" articles are preliminary or example articles.

When you are first refining your research topic and looking at the literature, you will most likely come across articles of interest that you know should be included in your review. These are referred to as exemplar articles. Exemplar articles can be used to test your search strategy and ensure that your search strategy is retrieving the kinds of literature you want to include in the review. In addition, citation chasing from exemplar articles is a great way to identify additional relevant literature. See below for some tools that can take advantage of your exemplar articles.